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赵磊,博士,中国科学院天津工业生物技术研究所研究员,博/硕士生导师。


科研领域及方向

从事植物细胞工程与代谢研究,致力于重要功能元件的发掘、设计与模块组装,并综合运用遗传学、细胞生物学、合成生物学等原理和方法,进行重要植物底盘细胞的理性设计改造及应用,以实现高附加值化学品、重组蛋白、天然产物等的绿色生物制造。


科研项目情况

[1] 天津市合成生物技术创新能力提升行动项目:重要植物底盘细胞的设计改造及应用,2021-2024

[2] 国家自然科学基金面上项目:水稻淀粉合成调控基因OsCLPB的作用机制研究,2021-2024


主要学术成果

先后发表各类科研论文10余篇,授权发明专利10项。发表的主要学术论文有:

[1] Zhao L, Hou YQ, Picariello T, Craige B, Witman G. Proteome of the central apparatus of a ciliary axoneme. The Journal of Cell Biology (2019) 218 (6) 2051-2070.

[2] Fu G*, Zhao L*, Dymek E, Hou YQ, Song KK, Phan N, Shang ZG, Smith EF, Witman G, Nicastro Daniela. Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus. The Journal of Cell Biology (2019) 218 (12) 4236-4251.

[3] Zhao L, Hou YQ, McNeill N, Witman G. The unity and diversity of the ciliary central apparatus. Philosophical Transactions of the Royal Society B. (2019) 375(1792):20190164.

[4] Zhao L, Cheng DM, Huang XH, Chen M, Dall’Osto L, Xing JL, Gao LY, Li LY, Wang YL, Bassi R, Peng LW, Wang YC, Rochaix JD, Peng LW, Wang YC, Huang F. A light harvesting complex-like protein in maintenance of photosynthetic components in Chlamydomonas. Plant Physiology (2017) 174: 2419-2433.

[5] Zhao L, Chen M, Cheng DM, Yang HM, Sun YL, Zhou HY, Huang F. Different B-type methionine sulfoxide reductases in Chlamydomonas may protect the alga against high-light, sulfur-depletion or oxidative stress. Journal of Integrative Plant Biology (2013) 55: 1053-1067.

[6] Kai Cai, Zhao L*, Zhao YH*, Daniela N, Witman G. Structural organization of the C1b projection within the ciliary central apparatus. Submitted to the Journal of Cell Science (2020)  

[7] Xing JL, Liu P, Zhao L, Huang F. Deletion of CGLD1 Impairs PSII and Increases Singlet Oxygen Tolerance of Green Alga Chlamydomonas reinhardtii. Frontiers in Plant Science (2017) 8: 2154.

[8] Chen M, Zhang J, Zhao L, Xing JL, Peng LW, Kuang TY, Rochaix JD, Huang F. Loss of algal Proton Gradient Regulation 5 increases reactive oxygen species scavenging and H2 evolution. Journal of Integrative Plant Biology (2016) 58: 943-946.

[9] Yang HM, Liao LB, Bo TT, Zhao L, Sun XW, Norling B, Huang F. Slr0151 in Synechocystis sp. PCC 6803 is required for efficient repair of photosystem II under high-light condition. Journal of Integrative Plant Biology (2014) 56: 1136-1150.


授权发明专利主要有:

[1] 黄芳、张锦、陈梅、赵磊,蛋白质PGR5在调控藻类抗氧化性中的应用,专利号:CN201510727193.5

[2] 黄芳、赵磊、程冬梅,一种能提高植物光合效率的莱茵衣藻蛋白E6及其编码基因与应用,专利号:CN201410490550.6

[3] 黄芳、赵磊、陈梅、张锦,一株超高放氢藻株及其应用,专利号:CN201410014492.X

[4] 黄芳、陈梅、赵磊、张锦,一种高产氢莱茵衣藻蛋白及其编码基因与应用,专利号:CN201410108048.4

[5] 黄芳、赵磊、杨浩萌,抗氧化及营养胁迫相关蛋白及其编码基因与应用,专利号:CN201210479314.5

[6] 黄芳、赵磊、程冬梅,具有光保护功能的蛋白及其编码基因与应用,专利号:

CN201210479164.8

[7] 黄芳、赵磊,提高衣藻产氢量的培养基及其制备方法, 专利号:CN201110230908.8

[8] 黄芳、赵磊、杨浩萌,用于扩增产氢微藻莱茵衣藻插入突变基因侧翼序列的引物及方法,专利号:CN201110026604.X

[9] 黄芳,吴骊珠,王红艳,陈梅,孙永乐,赵磊,陈彬,一种利用光合微藻高效筛选放氢催化剂法,专利号:CN201110100773.3

[10] 黄芳、赵磊、陈梅、孙永乐,一种高效筛选衣藻放氢突变体的方法,专利号: CN201010233108.7


联系方式

办公地点:天津空港经济区西七道32号中国科学院天津工业生物技术研究所

邮政编码:300308

办公电话:022-24828786

Email: zhaol@tib.cas.cn