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李文超,澳门威泥斯人讲师。20191月毕业于天津大学,获工学博士学位。


主讲课程

本科生:生物分离工程

研究生:生物反应工程


科研领域及方向

[1] 生物质炼制,致力于木质纤维素的高效生物转化(预处理机理、酶解过程、五六碳糖共发酵转化研究)

[2]合成生物学,致力于基于合成生物学的天然产物、生物能源、生物基化学品微生物制造。

[3] 发酵食品生物技术,致力于功能性食品开发。


科研项目情况

[1] 国家自然科学基金(22108205)木糖和纤维二糖共利用木葡糖醋杆菌的构建与调控研究,2022.01-2024.12。主持。

[2] 天津市高等学校基本科研业务资助项目 乙二胺预处理强化木本类木质纤维素酶解的机制研究,2020.01-2022.12。主持。

[3] 省部共建食品营养与安全国家重点实验室开放课题 (SKLFNS-KF-201911) 基于微生物发酵去除枸杞单糖的安全与营养评价研究, 2019.12-2020.11,主持。

[4] 国家自然科学基金面上项目 (21576198) 木糖利用的细胞记忆机制研究,2016.01-2019.12。负责基因工程酵母木糖代谢与环境间作用的研究,建立快速有效利用木糖的新型发酵工艺,驯化木糖菌株耐受抑制剂。参与。

[5] 国家重点基础研究发展计划“973”计划 (2013CB733601) 生物原料高效转化机制与调控规律, 2013.01-2017.12。研究预处理后残留乙二胺对酶解过程的影响,解决了木糖减少的问题;研究固液比对预处理的影响。参与。

[6] 国家优秀青年科学基金 (21622605) 生物质生物转化,2017.01—2019.12。研究乙二胺预处理对木质素的影响,并对其进行表征,研究木质素高附加值产品转化。参与。

[7] 国家重点基础研究发展计划“973”项目(2014CB745100) 微生物多细胞体系的设计与合成,2014.01-2018.12。参与。


主要学术成果

先后发表各类科研论文26篇,授权发明专利1项。担任《Energy》《Energy Conversion and Management》《Energy Sources, Part A: Recovery, Utilization, and Environmental Effects》《Bioresources and Bioprocessing》《Journal of Food Science》等杂志审稿人,发表的主要学术论文有:

[1] Li WC1, Li X1, Qin L, Zhu JQ, Han X, Li BZ*, Yuan YJ. Reducing sugar loss in enzymatic hydrolysis of ethylenediamine pretreated corn stover. Bioresource Technology 2017, 224:405-10.

[2] Li WC, Li X, Zhu JQ, Qin L, Li BZ*, Yuan YJ. Improving xylose utilization and ethanol production from dry dilute acid pretreated corn stover by two-step and fed-batch fermentation. Energy 2018, 157: 877-85.

[3] Li WC, Zhu JQ, Zhao X, Qin L, Xu T, Zhou X, Li X, Li BZ*, Yuan YJ. Improving co-fermentation of glucose and xylose by adaptive evolution of engineering xylose-fermenting Saccharomyces cerevisiae and different fermentation strategies. Renewable Energy 2019, 139:1176-83.

[4] Li WC, Zhang SJ, Xu T, Sun MQ, Zhu JQ, Zhong C, Li BZ*, Yuan YJ. Fractionation of corn stover by two-step pretreatment for production of ethanol, furfural, and lignin. Energy 2020, 117076.

[5] Li WC, Zhang SJ, Zhang TZ, Shen YQ, Han LJ, Peng ZJ, Xie ZX, Zhong C*, Jia SR, Bacterial cellulose production from ethylenediamine pretreated Caragana korshinskii Kom. Industrial Crops & Products 2021, 164:113340.

[6] Li WC, Han LJ, Peng TB, Xie YY, Zou Y, Li LZ, Jia SR, Zhong C*, Structural and behavior changes of herbaceous and hardwood biomass during steam explosion pretreatment and enzymatic hydrolysis. Bioresources 2020, 15:691-705.

[7] Li WC, Lv JG, Dong TY, Li XY, Li XN, Tan ZL*, Jia SR*, Effects of Amino Acids and Overexpression of dapA Gene on the Production of ε-Poly-L-lysine by Streptomyces diastatochromogenes Strains. Current Microbiology 2021,78(7): 2640-2647. DOI: 10.1007/s00284-021-02510-z

[8] Zhang TZ, Shen YQ, Zhang SJ, Xie ZX, Cheng XY, Li WC*, Zhong C*, Monosaccharide removal and effects of Komagataeibacter xylinus fermentation on antioxidant capacity and flavor profile of Chinese wolfberry juice. Journal of Food Processing and Preservation 2021.

[9] Li, WC; Liu, Y; Zhang, Q; Tan, ZL; Jia, SR*, Effect of CaCl2 on the stability and antimicrobial activity of nisin. IOP Conference Series: Earth and Environmental Science 2021, 705(1): 012011.

[10] Qin L, Li WC, Zhu JQ, Liang JN, Li BZ*, Yuan YJ. Ethylenediamine pretreatment changes cellulose allomorph and lignin structure of lignocellulose at ambient pressure. Biotechnology for Biofuels 2015, 8:174.

[11] Qin L, Li WC, Liu L, Zhu JQ, Li X, Li BZ*, Yuan YJ. Inhibition of lignin-derived phenolic compounds to cellulase. Biotechnology for Biofuels 2016, 9:70.

[12] Qin L, Liu L, Li WC, Zhu JQ, Li BZ*, Yuan YJ. Evaluation of soluble fraction and enzymatic residual fraction of dilute dry acid, ethylenediamine, and steam explosion pretreated corn stover on the enzymatic hydrolysis of cellulose. Bioresource Technology 2016, 209:172-9.

[13] Qin L1, Zhao X1, Li WC, Zhu JQ, Liu L, Li BZ*, Yuan YJ. Process analysis and optimization of simultaneous saccharification and co-fermentation of ethylenediamine-pretreated corn stover for ethanol production. Biotechnology for Biofuels 2018, 11:118.

[14] Zhu JQ, Li WC, Qin L, Zhao X, Chen S, Liu H, Liu ZH, Zhou X, Li X, Li BZ,* Yuan YJ. Stepwise pretreatment of aqueous ammonia and ethylenediamine improve enzymatic hydrolysis of corn stover. Industrial Crops and Products 2018, 124:201-8.

[15] Zhu JQ, Wu XL, Li WC, Qin L, Chen S, Xu T, Liu H, Zhou X, Li X, Zhong C, Li BZ,* Yuan YJ. Ethylenediamine pretreatment of corn stover facilitates high gravity fermentation with low enzyme loading. Bioresource Technology 2018, 267:227-34.

[16] Zhu JQ, Qin L, Li WC, Zhang J, Bao J, Huang YD, Li BZ*, Yuan YJ. Simultaneous saccharification and cofermentation of dry dilute acid pretreated corn stover at high dry matter loading: Overcoming the inhibitors by nontolerate yeast. Bioresource Technology 2015, 198:39-46.

[17] Zhu JQ1, Zong QJ1, Li WC, Chai MZ, Xu T, Liu H, Fan H, Li BZ,* Yuan YJ. Temperature profiled simultaneous saccharification and co-fermentation of corn stover increases ethanol production at high solid loading. Energy Conversion and Management 2020, 205:112344.

[18] Zhu JQ1, Li X1, Qin L, Li WC, Li HZ, Li BZ*, Yuan YJ. In situ detoxification of dry dilute acid pretreated corn stover by co-culture of xylose-utilizing and inhibitor-tolerant Saccharomyces cerevisiae increases ethanol production. Bioresource Technology 2016, 218:380-7.

[19] Qin L, Li X, Liu L, Zhu JQ, Guan QM, Zhang MT, Li WC, Li BZ*, Yuan YJ. Dual effect of soluble materials in pretreated lignocellulose on simultaneous saccharification and co-fermentation process for the bioethanol production. Bioresource Technology 2017, 224:342-8.

[20] Qin L, Li X, Zhu JQ, Li WC, Guan QM, Zhang MT, Xu H, Li BZ*, Yuan YJ. Optimization of ethylenediamine pretreatment and enzymatic hydrolysis to produce fermentable sugars from corn stover. Industrial Crops and Products 2017, 102:51-7.

[21] Liu H1, Zhu JQ1, Li X, Li HZ, Qin L, Li H, Wang X, Bai X, Li WC, Li BZ*, Yuan YJ. Hybridization improves inhibitor tolerance of xylose-fermenting Saccharomyces cerevisiae. Bioresources 2017, 12:4737-53.

[22] Qin L, Li WC, Zhu JQ, Li BZ, Yuan YJ. Hydrolysis of lignocellulosic biomass to sugars. In: Fang Z, Smith, Jr R, Qi X (eds) Production of platform chemicals from sustainable resources. Biofuels and Biorefineries. Springer, Singapore, 2017.

[23] An XJ, Xu J, Li F, Cao YX, Chen YY, Wu DG, Li WC, Guo XW, Lin X, Li CF, Liu SX, Song H*. Engineering microbial consortia for high-performance cellulosic hydrolysates-fed microbial fuel cells. Frontiers in Microbiology 2019, 10:409.

[24] Xu L, Li WC, Xin JY, Zhang SJ, Li BZ*, Yuan YJ. Ethylenediamine Enhances Ionic Liquid Pretreatment Performance at High Solid Loading. ACS Sustainable Chemistry and Engineering 2020, 8, 13007-18.

[25] Liu LP, Y X, Zhao XJ, Zhang KY, Li WC, Xie YY, Jia SR, Zhong C*. A Lambda Red and FLP/FRT-Mediated Site-Specific Recombination System in Komagataeibacter xylinus and Its Application to Enhance the Productivity of Bacterial Cellulose. ACS Synthetic Biology 2020.

[26] 张天震; 刘伶普; 李文超; 贾士儒; 钟成,群体感应系统介导细菌生物膜形成的研究进展。生物加工过程 2020, 18:177-83


授权发明专利主要有:

[1] 元英进;李文超;秦磊;朱家庆;李炳志;一种玉米秸秆的预处理方法,CN104561183B

联系方式

办公地点:天津经济技术开发区第十三大街29号澳门威泥斯人

邮政编码:300457

真:022-60602298


Emailliwenchao@tust.edu.cn